Recommended in Some Situations for People 18 Years and Older
In most situations, Pfizer-BioNTech or Moderna COVID-19 vaccines are preferred over Johnson & Johnson’s Janssen (J&J/Janssen) COVID-19 vaccine. J&J/Janssen should only be considered in some cases. J&J/Janssen COVID-19 vaccine cannot be used as a 2nd booster dose.
Primary Series: 1 dose of J&J/Janssen. People who are moderately or severely immunocompromised (have a weakened immune system) should get a 2nd dose of Pfizer-BioNTech or Moderna at least 4 weeks after their 1st dose in the primary series.
Boosters: People who received a J&J/Janssen primary series should get a booster. Only some people can get a 2nd booster dose. Use CDC’s COVID-19 booster tool to learn if and when you can get boosters to stay up to date with your COVID-19 vaccines.
Learn about the recommended timing between the J&J/Janssen COVID-19 vaccine and boosters for: