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Week 0 college football picks, odds, 2022 best bets from proven expert: This three-leg parlay returns 6-1

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Football dominates the TV landscape in American sports, and the country’s fervor for the game has led the college football season to begin earlier than ever in recent years. The Week 0 college football schedule will give fans a dose of the action beginning with Western Kentucky vs. Austin Peay on CBS Sports Network at noon ET. Meanwhile, the two of the marquee matchups on Saturday will be Nebraska vs. Northwestern in Dublin, Ireland at 12:30 p.m. ET and then Vanderbilt visiting Hawaii for a 10:30 p.m. ET kickoff, also on CBS Sports Network.

The Cornhuskers are 13.5-point favorites over the Wildcats in the latest Week 0 college football odds while the Commodores are 9-point favorites over the Rainbow Warriors in the only game to feature an SEC team in Week 0. So which teams should you be backing as you prepare to place your Week 0 college football picks? Before locking in any college football bets, be sure to see the top Week 0 college football expert picks, predictions and best bets from Barrett Sallee.

Sallee is a true insider — a CBS Sports analyst, SiriusXM host, Heisman voter and consistently one of the top CBS Sports experts picking games against the spread — and his best bets have helped bring in huge returns. He debuted with SportsLine in 2017 and has delivered in a big way on his college football picks

Over the past three years, he is 105-89 in his popular best bets column at SportsLine. Anybody who has been following him is way up.

Now, he has turned his attention to the Week 0 college football odds from Caesars and is sharing his top three best bets over at SportsLine. If you parlay them together, you could be looking at a return of around 6-1. Get his top college football picks now

Top Week 0 college football expert predictions

One of Sallee’s top college football picks for Week 0: He’s backing Illinois (-11) against Wyoming in a 4 p.m. ET matchup on Saturday. The Fighting Illini showed some fight toward the tail end of Bret Bielema’s first season running the program, winning four of their final seven games to finish the season at 5-7.

Meanwhile, Wyoming is coming off a 7-6 season under Craig Bohl, but took heavy losses in the transfer portal this offseason with leading receiver Isaiah Neyor and leading rusher Xazavian Valladay both leaving as well as quarterbacks Sean Chambers and Levi Williams. The Cowboys will only welcome back 34 percent of their production from last season, ranking 129th out of 131 FBS teams.

Bielema’s squad will welcome 54% of its production back from last season (103rd) but the program is hoping for a boost from former Syracuse quarterback Tommy DeVito and a recruiting class that finished in the top 50 in the 247Sports composite rankings. The defense ranked No. 29 nationally in points allowed last season and welcomes five of its top seven tacklers back, which is a big reason why Sallee likes the Fighting Illini to cover the double-digit spread at home. See who else Sallee likes at SportsLine.

Featured Game | Illinois Fighting Illini vs. Wyoming Cowboys

How to make Week 0 college football picks 

Sallee has also found two other college football picks he’s high on, including a double-digit underdog he believes has a chance to win outright. You can only see his picks at SportsLine.

What are the best bets for Week 0 of college football? And which college football picks need to be part of your parlays? Visit SportsLine now to see Barrett Sallee’s college football best bets, all from one of the top analysts in the nation who has crushed his picks for SportsLine.



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